I think its worthwhile running after and failing in big things. Rather than run after and fail in small things. Big upsides, Big downsides. At least the effort and lessons are worth the struggle.
Salman Rushdie said "Go for broke" - do whatever it takes to get out there and do things to the maximum even if the downside is huge. Because then, so is the upside.
I'll try to go after the big games. "To hunt the lions, you have to run with the wolves". Dont know if I read it somewhere, or it just popped up in my head. Doesnt matter. It makes sense.
P.S. Full quote by Salman Rushdie - "Go for broke. Always try and do too much. Dispense with safety nets.Take a deep breath before you begin talking. Aim for the stars. Keep grinning. Be bloody-minded. Argue with the world."